BPC 157 Stable Veterinary Therapeutic indications
Based on positive results in our animal studies with BPC 157 Stable we have determined for Veterinary use most useful indications of BPC 157 Stable which would be further needed to evaluate in Veterinary Clinical trials:
BPC 157 Stable for healing of animal gastrointestinal tract related diseases
Gastrointestinal tract related disease
Ulcers in any part of the gastrointestinal tract, general anti-inflammatory activity, gastrointestinal inflammatory disease
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Gastrointestinal lesions healing (lesions induced by NSAIDs, alcohol, cytostatic drugs) | Positive |
In studies we have demonstrated that BPC 157 may equally counteract both COX-1 and COX-2 inhibition (counteracting the noxious effects of standard NSAIDs and celecoxib on all lesions) and additional NOS blockade. Published in Eur J Pharmacol, Life Sci, Dig Dis Sci, World J Gastroenterology, Plos One.
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Duodenal ulcers healing
| Positive |
Therapy with BPC 157 Stable reduced duodenal lesions with evident healing effect. Published in Eur J Pharmacol, J Physiol, Inflammopharmacology.
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Ischemia and reperfusion colitis healing
| Positive |
In the study we have obtained new insights in treatment of colitis and ischemia and reperfusion in rats using stable gastric pentadecapeptide BPC 157. BPC 157 proved to be a fundamental treatment that quickly restores blood supply to the chemically injured area and rapidly activates collaterals and counteracts reperfusion injury. This effect involves the NO system. Published in World J Gastroenterology.
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Fistula healing (external and internal) | Positive |
BPC 157 Stable produces simultaneous healing of different tissues, thereby, it exhibits also excellent healing of fistulas, external and internal, colocutaneous, gastrocutaneous, esophagocutaneous, duodenocutaneous, vesicovaginal, colovesical, and rectovaginal. Published in J Pharm Sci, Eur J Pharmacol, Life Si, Dig Dis Sci, Cur Pharm Des, Biomedicines.
BPC 157 Stable for accelerated healing of animal wounds, muscles and nerve linkages
Accelerated healing of wounds, muscle, tendon, ligament, regeneration of ruptured nerve linkages
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Wounds healing (Wounds, Fistulas, Perforation, Skin Defects) | Positive |
In BPC 157 studies, reviewed was a particular skin wound therapy, incision/excision wound, diabetic ulcers, etc. which may be generalized to other tissues healing. Besides, the fully accomplished wound healing means that all four events, the vessel constriction, the primary platelet plug, the fibrin mesh which acts to stabilize the platelet plug, and the resolution of the clot, were all distinctively affected given the healing improvement by BPC 157 therapy in either early course or late course of wound healing. Published in Frontiers in Pharmacology, Journal of Physiology-Paris, etc.
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Muscles, ligaments and junctions healing (Muscle Crush, Muscle Transection, Myotendinous Junctions) | Positive |
Recovery of the myotendinous junction after detachment of quadriceps muscle from quadriceps muscle tendon and full function recovery can be seen as combined results of the previous recovering effect on muscle disturbances (muscle transection, crush, denervation) and tendon (transection, detachment, osteotendon junction recovery). Published in Biomedicines, Journal of Orthopaedic Research, Surgery Today.
BPC 157 Stable for healing animal Achilles' tendon injury
Accelerated healing of bone fractures, Achilles’ tendon
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Achilles’ tendon accelerated healing
| Positive |
BPC 157 therapy of Achilles tendon healing means the tendon recovery without ossicle formation after tendon transection as well as after tendon detachment from the bone, and osteotendon junction reestablishment. The bone healing effect includes bone recovery following severe pseudoarthrosis and bone loss. Published in Journal of Orthopaedic Research
BPC 157 Stable for healing of animal spinal cord injury
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Spinal cord injury healing
| Positive |
In Studies for Spinal cord injury healing we have demonstrated rapid and sustained recovery (1 year) and in addition we showed the particular points of the immediate effect of the BPC 157 therapy that began rapidly after its administration. Published in Current Issues in Molecular Biology, Journal of Orthopaedic Research
BPC 157 Stable for healing of animal eye diseases
Treatment of Glaucoma, Retinal Ischemia, Corneal ulcer therapy
Study Drug | Indication | Study results |
|---|---|---|
BPC 157 Stable – DIAGEN | Healing eye disturbances (Corneal ulcer therapy, Glaucoma, Retinal Ischemia) | Positive |
We revealed BPC 157 stable cytoprotective therapy with strong vascular rescuing capabilities in glaucoma therapy. With these capabilities, BPC 157 Stable therapy can recover glaucoma, normalize intraocular pressure, maintain retinal integrity, recover pupil function, recover retinal ischemia, and corneal injuries, maintain transparency after complete corneal abrasion, corneal ulceration, and counteract dry eye after lacrimal gland removal or corneal insensitivity. Published in Front Pharmacol, Pharmaceuticals, Exp Eye Res, Biomedicines.
